Follow us on

Our blog

Sep 06, 2022

Can Platelet-Rich Plasma Injections Delay the Need for a Knee Replacement?

In a recent study by Sánchez et al. they studied whether platelet rich-plasma or PRP could postpone or even be avoid TKA in patients with knee osteoarthritis.

In this study, the authors performed a retrospective study to determine how long patients were able to delay or avoid a total knee replacement. Of 1084 patients, 667 were included in the study. Out of these patients, 74.1% of the patients were able to delay a TKA for more than 1.5 years and the median delay was 5.3 years. During the 5-year study follow-up 85.7% of patients did not undergo a TKA. The authors found that the severity degree, age, PRP cycles, and administration route had a impact on how effective the PRP was in delaying surgery.

Overall, the findings of this study suggested that PRP intra-articular injections were helpful in delaying a total knee replacement in patients with knee arthritis.


Sánchez M., Jorquera C., Sánchez P., Beitia M., García-Cano B., Guadilla J., Delgado D. Platelet-rich plasma injections delay the need for knee arthroplasty: A retrospective study and survival analysis. Int. Orthop. 2021;45:401–410.

More Articles

Mar 02, 2023

Non-surgical Treatments for Lateral Epicondylitis and Medial Epicondylitis: Tenex versus Platelet-Rich Plasma

Medial epicondylitis (golfer’s elbow) and lateral epicondylitis (tennis elbow) are among the most common elbow pathologies affecting people aged between 40 and 50 years. Although epicondylitis is often a self-limiting

Read More
Feb 06, 2023

What is A2M and what is the data for A2M in Osteoarthritis?

Osteoarthritis is common problem causing joint disease. Alpha-2-macroglobulin (A2M), a naturally occurring macromolecule that is found in the blood serum, and studies have demonstrated that Alpha-2-Macroglobulin, or

Read More